The 8-month-old Bruce accidentally lost his penis when undergoing circumcision. His parents followed the advice of Manny, the master of sexology at the time, and transformed their Bruce into a girl and raised him as a daughter.
Under Manny’s instruction, the little Bruce, who was renamed Brenda, became a guinea pig for a scientific experiment. The control group was his twin brother Brian.
The experiment wanted to prove that gender identity is not inborn, but the result of nurturing. However, Brenda, who became a girl, felt trapped in a body that did not belong to her when she grew up, and she was incompatible with the outside world.